Technology Platform
Mass Spectrometry Metabolic Platform
Mass Spectrometry Metabolic Platform
LCMS-8050 Triple Quadrupole Liquid Mass Spectrometer
(Registration Certificate Number: National Machinery Injection 20182400195)
The LCMS8050 liquid chromatography-mass spectrometer is a re-evolution of Shimadzu's UF technology. High-sensitivity quantification can be achieved faster, multi-component simultaneous analysis is faster, and qualitative and quantitative analysis can be performed at the same time. The high performance of LCMS-8050 overturns existing common sense and realizes high sensitivity × high-speed analysis: UF scanning high sensitivity × high-speed scanning 30,000 u/sec simultaneously performs quantitative and qualitative, while ensuring quantitative accuracy, MS/MS can be performed Scanning and MRM quantification. Shimadzu uses a step frequency of 0.1u, which enables stable and reliable MS/MS scanning even at a speed of 30,000u/sec. The LCMS-8050 triple quadrupole liquid-mass spectrometry is used to accurately assist targeted metabolic analysis. Nanxin Medical Inspection Laboratory conducts targeted and specific detection and targeted metabolomics analysis with specific metabolite groups on this platform, mainly including: 15 bile acids, 15 short-chain fatty acids, 23 A group of metabolites such as amino acids and 19 vitamins.
The Agilent 6545 accurate mass Q-TOF LC/MS system can provide excellent sensitivity, resolution, mass accuracy, isotope fidelity and speed in a single measurement. The SWARM cluster auto-tuning function of the device improves the sensitivity of analysis by up to 5 times, and can retain unstable compounds, thereby improving detection. The system combines excellent sensitivity with quantitative accuracy in a wide dynamic range of the spectrum, which can reduce the number of repeated determinations required or reduce the scale of the study. Nanxin Medical Inspection Laboratory uses this platform for scientific research services such as non-target metabolism and metabolite identification.
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